Analytical Scientist
As an Analytical Scientist, the incumbent will be a core contributor to the development and characterization of antibody-based therapeutics. The scientist will design and implement analytical methods for early- to mid-stage development, with a focus on UPLC, CE, and binding assays. This is a hands-on lab role ideal for a PhD-level scientist who thrives in a dynamic, high throughput setting and is proficient in working cross-functionally.
Responsibilities
- Develop and execute robust analytical methods using UPLC (SEC, IEX, RP), CE (CE-SDS, cIEF), and binding assays (ELISA, BLI) to support antibody characterization. Maintain good documentation for all studies.
- Support cell line development, process development, formulation screening, comparability, and stability studies.
- Analyze, interpret, and communicate data to project teams in a timely and scientifically rigorous manner.
- Collaborate with upstream, downstream, and formulation scientists in an integrated CMC environment.
- Author high-quality technical reports, method protocols, and contribute to regulatory documentation.
- Evaluate new analytical technologies and help build internal capabilities as the company scales.
- Contribute to establishing a phase-appropriate analytical control strategy for lead candidates.Wear multiple hats, bring solutions, and help shape the analytical infrastructure as the company grows.
- PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline.
- 0–3+ years of relevant industry experience (biotech/pharma) in biologics analytical development and demonstrate strong teamwork.
- Strong technical background in HPLC/UPLC and CE techniques for therapeutic proteins.
- Hands-on experience with antibody binding assays (e.g., ELISA, SPR or BLI).
- Solid understanding of antibody structure, post-translational modifications, and critical quality attributes (CQAs).
- Comfortable working in a dynamic environment with shifting priorities and evolving needs.
- Excellent communication, organization, and problem-solving skills.
- Experience in tech transfer, method qualification, or early GMP readiness.
- Familiarity with software platforms like JMP, Empower, SoftMax Pro, or ForteBio Data Analysis.
- Passion for working in a mission-driven environment and building from the ground up.
Compensation and Benefits:
The expected base salary range for this position is $75,000 - $105,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise align strongly with the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.