PE - Research Associate/Sr. Research Associate, Protein Engineering

SystImmune Inc. is a dynamic clinical-stage bio-pharmaceutical company headquartered in Redmond, WA. Our mission is to revolutionize cancer treatment by developing breakthrough-therapeutic multi-specific antibodies and ADCs. With eight assets in ongoing clinical trials and a robust preclinical pipeline, we are committed to advancing innovative therapies from discovery through clinical development.

Job Summary:

We are seeking a highly skilled and motivated Research Associate or Senior Research Associate to join our Protein Engineering Group. The successful candidate will play a critical role in advancing our protein engineering efforts through numerous techniques, including molecular biology, protein purification, Biolayer interferometry (BLI), and protein stability measurements. Ideal candidates will have a strong background and interest in the properties and functions of proteins and protein-protein interactions. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.

Responsibilities:

• Protein Purification: Perform affinity chromatography, ion-exchange chromatography, and size-exclusion chromatography using FPLC systems.
• Protein Analytics: Conduct size-exclusion chromatography on HPLC systems to assess purity and stability.
• Mammalian Expression & Cell Culture: Transfect mammalian cells for protein expression and maintain cell lines.
• Molecular Biology: Utilize techniques such as Gibson Assembly, PCR, gel electrophoresis, DNA sequencing, and plasmid preparations.
• Data Analysis & Reporting: Analyze experimental data, generate reports, and present findings to cross-functional teams.
• Collaboration & Innovation: Work closely with multidisciplinary teams to contribute to project planning and execution.
• Lab Management: Maintain accurate records, ensure safety compliance, and support lab organization and operations.

Qualifications:

• Education: Bachelor’s or Master’s degree in biochemistry, molecular biology, structural biology, or a related field.
• 2+ years of laboratory experience, with at least 1+ year of industry experience in drug development preferred. 1+ years of hands-on experience in protein purification or molecular biology.
• Proficiency in protein purification and handling is required
• Experience with mammalian expression systems is strongly preferred.
• Strong background in molecular biology and biochemistry.
• Familiarity with data analysis software and statistical tools.
• Ability to maintain records within a laboratory information management system (LIMS).
• Excellent problem-solving and troubleshooting abilities.
• Strong organizational and time management skills.
• Ability to work independently and as part of a team.
• Effective verbal and written communication skills.

The hiring pay range for this position is $65,000 - $110,000 per year based on skills, education, and experience relevant to the role.

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery or IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.